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In addition, castration also increased the expression of ROS-production related genes such as Nox1 and GP91PHOX (the catalytic subunit of Nox2) and decreased the levels of antioxidant enzymes such as superoxide dismutase 2 (SOD2), glutathione peroxidase 1 (GPX1), thioredoxin, and peroxiredoxin 5 in the prostate alveolar epithelium of rats (125)

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Save Face, a register of accredited practitioners, said it had recorded 90 complaints about the product so far in 2023 50 in the past three months compared with just one complaint in the whole of 2022

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