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The first sign of degradation is a color shift from clear pale blue to greenish-brown, followed by haze or visible particulate

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One of the nutrient deficiencies that people with Hashimotos are particularly prone to is vitamin B12

The liver stores are a bit irrelevant to someone who has PA or a B12 absorption problem though because the mechanism that is used to release them relies on the same mechanism that is used to absorb most dietary B12 so accessing any stores is at best very inefficient

Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats