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Lower nocturnal melatonin levels and/or its urinary metabolite, 6-sulfatoxymelatonin, were found in migraine patients compared with healthy controls, and melatonin was shown to be more effective than placebo for the prevention of migraine in adults

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Clin Pharmacol Ther 58(2):210220 Yuan L, Kaplowitz N (2008) Glutathione in liver diseases and hepatotoxicity