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Early lab data shows that NNMT inhibition helps preserve nicotinamide, a compound the body uses to form NAD, which supports cell energy

Because MOTS-c enhances insulin-independent glucose uptake, patients with type 1 diabetes or those using exogenous insulin should be monitored carefully to prevent hypoglycemia, though this theoretical risk has not materialized in clinical reports to date

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Scientists investigate its role in modulating the methyl economy of the cell, particularly in adipocyte and metabolic tissue contexts

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