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Thus, evidence exists that ASD-like symptoms may be improved by targeting the vitamin E/vitamin C/glutathione network

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Recent research shows that supplementing with the pyridoxine form of B6 at higher doses can paradoxically inhibit the creation of P5P.[ref] Researchers think that excess pyridoxine from high-dose supplements leads to the inhibition of PDXK, the enzyme that converts pyridoxine to P5P

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[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Xie W., Ma W., Liu P., Zhou F