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[Link] Accordingly, our results indicate that ALCAR is transported from blood to brain ECF by OCTN2 at least in part, and its concentration in brain ECF is regulated by other events such as protein binding and anabolic reactions in the brain, as well as by transport across the BBB. Reuter, SE and Evans, AM, Carnitine and acylcarnitines: pharmacokinetic, pharmacological and clinical aspects. in Clinical Pharmacokinetics , Volume 51, Issue 9, pp 553 - 572

( 10.1007/BF03261931) [DOI] [PubMed] [Google Scholar] Rowe PJ, Comhaire FH, Hargreave TB, Mahmoud AMA.2000

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All these changes eventually collapses gelatinous structure of thick albumen into a clear liquid (albumen thinning) as albumen consistency is lost (9) as well as the rheological, nutritional and technological properties which consumers rely on