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GLP-1 glucagon-like peptide-1 is a hormone released by specialized cells in the gut lining called L-cells, primarily in response to food

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doi: 10.1007/s00394-021-02770-2 22 MaratheCSRaynerCKJonesKLHorowitzM

Semaglutide is a GLP-1 receptor agonist used for chronic weight management alongside a reduced-calorie diet and increased physical activity for people with a BMI of: 30 kg/m or greater (obesity), or 27 kg/m or greater (overweight) with at least one weight-related condition (e.g., hypertension, type 2 diabetes, dyslipidemia)