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Description
634 AAK1 inhibitor LX-9211: Junctional protein 2-associated kinase 1 (AAK1) is widely expressed in the brain and spinal cord and is a viable target for the treatment of neuropathic pain, and BMS-986176/LX-9211 is a novel class of bis(iso)aryl ethers that are highly selective, CNS-permeable, and potent AAK1 inhibitors
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A., Vichare, R., Paulson, R., Bhatia, S., Mohapatra, S., et al
Feb 2014;192(1):175-84
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doi: 10.1016/j.pbb.2011.09.002
