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[9,10] However, delayed recognition of SUM remains a concern, with reported cases being often diagnosed at advanced or metastatic stages

Dunn, "Apache Relations in Texas, 17181750," Quarterly of the Texas State Historical Association 14 (January 1911)

Our findings suggest potential therapeutic opportunities for targeting sphingomyelin levels to counteract NPC or other neurodegenerative diseases caused by disturbed cholesterol homeostasis

C Color: Uneven coloring, including shades of black, brown, tan, red, or white

Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress

Hence, there is insufficient evidence to confirm their impact in humans