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Statistical analysis was performed using one-way analysis of variance (ANOVA) to compare the experimental groups and Bonferroni's test was used to find significantly different groups (SPSS for Windows, version 17, SPSS Inc., Chicago, IL)

Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1

DNA was extracted from samples T 0 and T 1 , and CRISPR guide regions amplified by PCR, and sgRNA in each sample were sequenced using a U6 custom primer 57 on the HiSeq (Illumina) to generate gRNA count data

[DOI] [PubMed] [Google Scholar] 98.Sikiric P., Seiwerth S., Grabarevic Z., Rucman R., Petek M., Rotkvic I., Turkovic B., Jagic V., Mildner B., Duvnjak M., et al