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Experimental Autoimmune Encephalomyelitis (EAE) Model of Multiple Sclerosis Experimental autoimmune encephalomyelitis (EAE) in rodents is a common experimental model for the human demyelinating disease, multiple sclerosis, with some common key pathologic features of inflammation, axonal loss, and gliosis [336]

ROS-related anticancer mechanisms include mitochondrial dysfunction, p53-dependent apoptosis, iron-dependent ferroptosis, activation of endoplasmic reticulum stress, inhibition of growth signaling pathways (such as the epidermal growth factor pathway, EGF), among others

(PubMed) Seow A, Shi CY, Chung FL, et al

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