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Age compounds the problem
, & Rittmann, S
This review focuses on the antioxidant systems roles in maintaining redox homeostasis
Mainly, Alpha class GSTs, and in particular GSTA1-1, GSTA2-2, and GSTA3-3, are involved in this interaction, suggesting the existence of a protective enzyme barrier at the nuclear envelope, in which GSH plays an important role [56]
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In addition to serving as a substrate for histone acetylation, ethanol metabolism in the brain contributes to the synthesis of glutamine in astrocytes
