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Glucocorticoid-based enhancement of bone marrow adipogenesis with suppression of osteoblastogenesis is primarily mediated by the upregulation of adipogenic transcription factors including C/EBPs and PPAR with downregulation of osteogenic transcription factor RUNX2 in a dose- and time-dependent manner (207, 262, 288, 303, 387, 451)

Schwartz, M.D., Katherine Irby, M.D., Tamara T

Storage method and period of stock solution: -80C, 6 months

received honoraria from MSD, Yuhan