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Factors conferring relative protection to children from the toxic effect of paracetamol overdose include increases in paracetamol sulphation capacity [4448], relative immaturity of the CYP450 oxidation system [15, 46, 49, 51] and the larger relative liver volume found in children [59] but these theoretical mechanisms have not been confirmed

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Spectra data were log-transformed and weighted by an adaptive intensity weighting algorithm

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Abstracts Hooda Z,, Antonoff MB, Rice DC , Ries S, Mehran R, Mitchell KG, Rajaram R, Swisher S, Vaporciyan A, Walsh G, Hofstetter W