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p62: friend or foe

Never discontinue inhaled corticosteroids or other asthma medications without physician guidance

It's described as the "master antioxidant" because it does two jobs at once: it neutralises free radicals directly, and it helps recycle other antioxidants like vitamin C and vitamin E so they can keep working

Similarly, calcium imaging can record astrocytic Ca + signals but may miss rapid transient activities (225), while photoacoustic and bioluminescence imagings low sampling rates might overlook millisecond-scale signal fluctuations (226).At the experimental operation level, invasive devices such as fiber recording and two-photon imaging require head fixation or probe implantation, which not only restricts natural mouse behavior but may also activate local astrocytes (122, 125)

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Rosenfeld RJ, Goodsell DS, Musah RA, Morris GM, Goodin DB, Olson AJ (2003) Automated docking of ligands to an artificial active site: aumenting crystallographic analysis with computer modeling
