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4.2.1 GLP-1 and GLP-2 As core components of the incretin system, glucagon-like peptide-1 (GLP-1) secreted by intestinal L-cells not only regulates glucose metabolism through glucose-dependent insulin secretion enhancement and glucagon suppression but also induces weight loss via gastric emptying delay and appetite inhibition

[Google Scholar] Dote T, Kono K, Usuda K, Shimizu H, Tanimoto Y, Dote E, Hayashi S

The systemic support could amplify the localized effect

We found that processing the counts from the 2 cohorts together and correcting for batch effects with ComBat effectively harmonized the data from the 2 cohorts