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3.2 Sulforaphanes role in mitigating neuroinflammation Neuroinflammation is defined as an immune response within the central nervous system (CNS), characterized by the activation of microglia and astrocytes, increased pro-inflammatory cytokines, and potential disruption of neuronal homeostasis (DiSabato et al., 2016)

Diseases and pollutants disrupt these processes through altered ion transport, elevated pH and calcium, and goblet cell hyperplasia that leads to viscous mucus and airway obstruction

It is closely associated with metabolic disorders such as diabetes, cardiovascular diseases, non-alcoholic fatty liver disease, and certain types of cancer [1]

Woll and the Maryland E- Novation Initiative Fund to establish the Marcella E

A 71-year-old white, non-Hispanic, gravida 1 para 1 woman presented with one month of postmenopausal bleeding and vaginal discharge

For example, the NRF2-specific activator 4-octyl itaconate significantly reduces cisplatin-induced ferroptosis by activating the NRF2/HO-1 signaling pathway (Zhang et al., 2024)
