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Vernia S, Cavanagh-Kyros J, Barrett T, Tournier C, Davis RJ

Thus, RpiB is a potential therapeutic target for treating diseases such as African Sleeping Sickness, Chagas disease, and leishmaniasis

1.3.1 Cytoplasmic hybrid (cybrid) cell lines First derived in 1975 by Wallace, Bunn, and Eisenstadt, cytoplasmic hybrid (cybrid) cell lines are generated by the fusing of nucleated cells that have had their endogenous mtDNA depleted via exposure to ethidium bromide with enucleated cells (cytoplasts), which harbor the mtDNA signature of interest (Figure 3A

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They improved visual memory in 22 healthy people, attention and memory in 50 people with mild cognitive impairment, and visual learning, attention, and general fatigue in 44 people with chronic fatigue syndrome [78, 79, 80]

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