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High-intensity intervals may also have a role, but many patients benefit most from first building a reliable aerobic base

Here, we report that sulindac treatment induces autophagic cell death in GABAergic neurons via the PI3K/AKT/mTOR pathway, leading to hyperactive behaviour in zebrafish larvae and mice

Take photos and measurements, not just scale weight

The bulk of data sits in rodent models, with the brain-gut axis as the theoretical framework that connects the peripheral and central effects

Available online at: (Accessed October 6, 2025)

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