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Weight loss itself can occasionally trigger subtle changes in how your body handles certain micronutrients, though clinical trials have not shown widespread deficiency syndromes in short-term GLP-1 users

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Both enzymes, GPX7 and GPX8, are located in the endoplasmic reticulum and are necessary enzymes involved in the oxidative folding of endoplasmic reticulum proteins, and GPX8 also plays an important role in the regulation of Ca 2+ in the endoplasmic reticulum

J Bioenerg Biomembr (2001) 33(6):493501

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In younger individuals or those who lost weight gradually, the skin can sometimes remodel itself over 12 to 24 months