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By compromising mitochondrial turnover and quality in response to cold stress, defects in both mitophagy and mitobiogenesis brought on by the loss of FUNDC1 raise the possibility that maintaining the proper balance between these processes is essential in meeting the increased demand for mitochondrial function that arises in some tissues under diverse environmental pressures [230]

Chalcone-type chemicals, which include an ,-unsaturated carbonyl group, change the cysteine residues of Keap1 via Michael addition, stimulating Nrf2 [112]

The neuroprotective mechanisms of MEM in AD against neuronal loss (apoptosis decrease and mitochondrial alteration) and reduction of A production could be attributed, at least in part, to its selective action blocking extrasynaptic NMDAR

Unravelling crucial biomechanical resilience of myelinated peripheral nerve fibres provided by the Schwann cell basal lamina and PMP22

Cookson, B

Also, melanogenic switching was found to be related to tyrosinase activity levels, where high tyrosinase activity produced an excess of dopaquinone resulting in the inactivation of GR and other enzymes essential for pheomelanogenesis [99]