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Do not use if tamper seal is damaged
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The rubber stopper is coring If small pieces of rubber break off into the vial when you insert the needle, you are using a needle that is too large or inserting it incorrectly

Paradis-Bas, M., Tulla-Puche, J

A large cohort study involving over 1.4 million transfusion recipients found no increased PD risk in those who received blood from donors later diagnosed with neurodegenerative diseases, supporting transfusion safety [291]
