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Over time, glutathione levels can naturally decline due to everyday pollutant exposure, smoking, stress, poor diet, intense physical exertion, aging, or persistent immune challenges

It is referred as the most critical antioxidant, shielding the body from the harmful effects of oxidants like cigarette smoke and alcohol consumption

These effects can be particularly harmful as they may synergistically promote the development of steatohepatitis when heavy drinking is combined with a high-fat diet (118)

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Roles of the Oxidative Stress and ADMA in the Development of Deep Venous Thrombosis