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Many NUS species exhibit structural features, such as high fiber content, variable moisture levels, and thick cell walls, that hinder solvent infiltration and compound release from the matrix

Others not

The influence of PEG chain length and targeting moiety on antibody-mediated delivery of nanoparticle vaccines to human dendritic cells

While generally well-tolerated, some patients may experience side effects

New Chin Med 2012;44:479

It is characterized by reduced BMD and compromised bone microarchitecture, ultimately leading to increased skeletal fragility and a higher incidence of fragility fractures (Mizoguchi and Ono, 2021