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Manifestations and mechanisms of stem cell aging
GSK3beta activity modifies the localization and function of presenilin 1
Although selenium was not measured in this study, adequate nutritional intake of selenium could potentially mask other differences between genotypes in this population
, & Barba, F
For example, the important MTHFR enzyme, which contains more than 500 amino acids and has a molecular weight exceeding 77,000, is susceptible to mutations [5]
Multidimensional Epistasis and Fitness Landscapes in Enzyme Evolution
