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In polarized cells, such as BCECs, endocytosis can occur at both the luminal and the basolateral plasma membranes
Several weeks others experience more gradual changes as red blood cell levels normalise
Ascorbyl 6-palmitate (A6P), a lipid-soluble ester analog of ascorbate, acts as an antioxidant in erythrocytes in vitro [50,51] and increases ascorbate concentration in neuronal tissues, suggesting A6P crosses the blood brain barrier [52]
doi: 10.1016/j.neuropharm.2014.02.006
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