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407,408 Therefore, developing effective therapies for metabolic disorders has become a focal point of research

It is intriguing though, that despite the mild impact on L-carnitine levels, patients affected by these diseases have marked brain alterations such as nondysmorphic autism (deficiency of 6- N -trimethyllysine dioxygenase) [60] and microcephaly and speech delay (deficiency of -butyrobetaine dioxygenase) [61]

S2CID 35899454

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Galiski M, Lewandowski A, Stpniak I

Intracellular and extracellular carnitine may be present as either non-esterified free carnitine (FC) or as esters of short-, medium-, or long-chain organic and fatty acids