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Description
V-9302, a promising small inhibitor specifically targeting SLC1A5, has been tested in preclinical models ( in vivo , suggesting that xCT is a common druggable target in TNBC tumors ( in vitro and in vivo , whereas GLS silencing has minimal effects on metabolic phenotype or growth in luminal cell lines
10 July 1968
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Many noteworthy reviews have been written highlighting general immunometabolism, contributions of select pathways, role of tissue-specific factors, and metabolism in defined subsets of cells (2124)
Rodent models offer various advantages, including small size, rapid reproduction, physiological similarities to humans, and ease of handling [81]
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