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Description
Recent studies have shown that at least one mechanism of colchicines action is by acting to prevent a cascade of reactions that lead to the production of interleukin 1-beta, which is an inflammatory protein (cytokine), which is important in gouty inflammation.8 When used as one or two tablets a day (0.6mg each), most people tolerate this medication well, and this dose can help prevent gout attacks

Brazilian Journal of Microbiology, 44 , 341

doi: 10.1093/bib/bbs046

CellTiter-Glo Luminescent Cell Viability Assay was purchased from Promega (Leiden, Netherlands)

Acknowledgements GK is supported by the Ligue contre le Cancer (quipe labelise)
doi: 10.1016/j.jpba.2021.114276 152 MekkawyMHFahmyHANadaASAliOS
