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MLCK1 expression and enzymatic activity can be activated by cytokines that include IL-1 and tumour necrosis factor (TNF) 124,125,135,140,158,295

Chemosphere 168 , 501507 (2017)

According to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), there are two main symptom or characteristic areas of ASD: Deficits in social communication and interaction Restricted, repetitive behaviors (such as stimming), interests, or activities Some potential characteristics of ASD include, but are not limited to: Differences in eye contact Differences in body language Strong preference for routine and predictability Repeating gestures or sounds Closely focused interests Fewer facial expressions Decreased awareness of temperature extremes Although someone may present with some or all of the above characteristics, this does not automatically mean they have autism

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Dit betekent dat het langer duurt voordat de effecten beginnen op te treden

10.1186/s12943-017-0589-8 162 NwaeburuC