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neoformans has a multiple-hit intracellular survival strategy, resulting in the progressive deterioration of host cellular functions

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Supplementary Material Acknowledgments This work was supported by grants from the National Sciences Foundation of China (32570485, 31770384 and 21605164), the Key Research and Development Program of Zhejiang Province (2025C01135), the Huayi Technology Innovation Center for Research Resources (HTIC P01 RR2017001A), and the Key Laboratory Construction Funds of State Ethnic Affairs Commission of China (10301-02200303)

The energy-boosting effect is only seen when treating genuine deficiency, where fatigue is a primary symptom