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The treatment area is first made comfortable with a numbing solution that is introduced into the skin through two tiny incisions, about the size of the tip of a pen

Kajiwara 1995

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showed that co-expression of PDZD8 and Protrudin induces abnormally large vacuoles, proposing a model whereby PDZD8 transports lipids from the ER to late endosomes 72

Elamipretide treatment was also shown to increase ADP sensitivity in vivo and decrease ROS production in vitro (Pharaoh et al., 2023)

Trends in neurosciences 30 , 7984, doi:10.1016/j.tins.2006.12.002 (2007)