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One molecule of GSH reduces the selenenic acid, leading to the formation of a glutathiolated selenol (Se-SG) intermediate (127, 204, 248)

After incubation in 0.1% Triton-FACS buffer for 30 min, permeabilized cells were incubated with a primary antibody against ABCC1 (anti-MRP1, ab24102, lot: GR284248-19, Abcam, UK

Takahashi K, Wang F, Morita K, Yan Y, Patel K, Bueso-Ramos CE, Gumbs C, Zhang J, Kornblau S, DiNardo CD, Ravandi F, Garcia-Manero G, Jabbour EJ, Andreeff M , Kantarjian HM, Konopleva M, Futreal A

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