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Preclinical studies also suggest potential efficacy against Pneumocystis jirovecii ( El Ayoubi et al., 2024)
Furthermore, exploiting antioxidant vulnerabilities through aldehyde dehydrogenase (ALDH) inhibition with agents like disulfiram, or glutathione peroxidase 4 (GPX4) inhibition, can induce ferroptosis specifically in DTP populations, further reducing residual tumor burden (Raha et al., 2014)
10.1016/S0022-3913(10)60081-9 [DOI] [PubMed] [Google Scholar] Timn-Gmez A, Nvltov E, Abriata LA, Vila AJ, Hosler J, & Barrientos A (2018)
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