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GluN2C subunit is critical to normal cortical neuronal oscillations Due to their unique biophysical properties such as reduced voltage-dependency due to a lower sensitivity to Mg 2+ -blockade as well as lack of desensitization 17 , GluN2Ccontaining receptors may be active without the requirement for prior depolarization and via spillover glutamate thereby leading to tonic activity, which can impact neuronal oscillations

Biomaterials 2024 , 308 , 122542

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