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Recordings were obtained using a Multiclamp 700B amplifier (Molecular Devices, Sunnyvale, CA), Analog signals were low-pass Bessel filtered at 2 kHz, digitized at 10 kHz through a Digidata 144 OA interface (Molecular Devices), and stored in a computer using Clampex 10.2 software (Molecular Devices)

Cyclical changes in E2 and P4 alter hypothalamicpituitaryadrenal (HPA) axis sensitivity, modifying cortisol dynamics, stress perception, and emotional reactivity across the cycle [56]

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MOHANDAS, J., DUGGIN, G.G., HORVATH, J.S., & TILLER, D.J

They work at complementary levels: Epitalon addresses chromatin structure and telomere biology, while GHK-Cu resets gene expression patterns across thousands of genes

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