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For the HDL-C quartiles, with the exception of the increase in AST/ALT with increasing quartiles, other measures decreased, and the higher HDL-C groups were more likely to be female, younger, and less prone to diabetes, hypertension, and hyperuricemia (all P 2.19 mmol/L, this protective relationship disappears, which also indicates that higher HDL-C is not always good (44)

Oram JF, Wolfbauer G, Vaughan AM, Tang C, Albers JJ

Patrone V, Puglisi E, Cardinali M, Schnitzler TS, Svegliati S, Festa A, et al

(2009) Clostridium difficile infection: new developments in epidemiology and pathogenesis

Why it happens: The rise of obesity in T1D is shaped by global lifestyle trends, genetics, and epigenetics , but also by treatment itself