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Paldino, E

An early study demonstrated a protective effect of UA on spontaneous death of dopaminergic neurons in culture, with an antioxidant mechanism targeting Fe-produced reactive oxygen species 37

Certain medications, such as metformin used for diabetes
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[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Zhang R, Hess DT, Qian Z, Hausladen A, Fonseca F, Chaube R, Reynolds JD, Stamler JS

10.1016/j.comptc.2015.07.016 355 YeZ.-W.ZhangJ.AncrumT.ManevichY.TownsendD

Takeaway: Purely preclinical data at this stage
