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Due to their cytotoxic effects, the majority of HDACis are approved for use in hematological and neoplastic malignancies [89]

Repeated-measure ANOVA was used to determine statistically significant changes between groups over time

The 5xFAD mouse line has five mutations: the Swedish (K670N/M671L), Florida (I716V), and London (V717I) mutations in APP, as well as the M146L and L286V mutations in PSEN1

2.7 MRS data analysis Data were preprocessed and quantified using Gannet v3.3.0 (Edden et al., 2014)

These substances can reach the submucosal layer, contributing to intestinal pathologies and systemic pro-inflammatory responses (4951)