human glutathione synthetase residues in Brain Disorders and Aging RCSB PDB - 2HGS: HUMAN

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Since glutathione (GSH) depletion (about 20% of total GSH content) can impair the cell's defence against the toxic actions of drugs and may lead to cell injury and death, we examined the effect of piroxicam, naproxen and ketoprofen on GSH levels in various organs of the rat (brain, eye, liver, stomach, heart, leg adductor muscle)

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Research has shown that glutathione is essential for neutralizing reactive oxygen species, supporting mitochondrial function, and maintaining cellular homeostasis

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