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The effects of prebiotics on gastrointestinal side effects of metformin in youth: A pilot randomized control trial in youth-onset type 2 diabetes

The guidelines were established by the Consort statement and were established for each section of a RCT report: enrolment, intervention allocation, follow-up, and analysis) [6]

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Additional biomarkers such as homocysteine and methylmalonic acid (MMA) were also considered to evaluate functional deficiency

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Reference lists from review articles and key case series were screened for additional hits and members of the guideline group were asked to suggest relevant book chapters