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Acknowledgements Financial support from the German Federal Ministry of Education and Research (BMBF) within the framework of the e:Med research and funding concept for SysMedOS project (to MF), Sonderzuweisung zur Untersttzung profilbestimmender Struktureinheiten 2021 by the SMWK, and Deutsche Forschungsgemeinschaft (FE 1236/5-1 to MF) are gratefully acknowledged

It is also important to note that a prior randomized, placebo-controlled, double-blind study of LAC treatment for probable AD patients showed that administration of LAC was associated with lower AD-related deterioration as assessed using the clinical dementia rating scale and mini-mental scale examination in those subjects younger than 65 years [65, 66]

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These records and histologic data were entered into a centralized database ( The following variables were compared among the three cohorts (NF1-associated, radiation-associated, and sporadic malignant peripheral nerve sheath tumor): NF1 status, age at diagnosis, gender, tumor location, tumor size, depth location, histologic subtype, and tumor grade (FNCLCC)

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