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One mutated and one normal MTHFR copy: You inherit the mutated version (gene with a change or a variant) from one parent and the normal version from the other - this is called the heterozygous state
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Thus, dysregulation of AGE-RAGE axis results in different aberrant biological/physiological processes leading to neurodegeneration
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doi: 10.1021/acsnano.5c00574 340 JiangRYangLLiuXXuYHanLChenYet al
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