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That means: Hypokalemia can develop or worsen which can lead to: Cardiac arrhythmias Muscle weakness QT prolongation In severe cases, sudden cardiovascular instability This is a classic board-style pearl that many clinicians forget because B12 feels benign. But in profoundly deficient patientsespecially those with severe megaloblastic anemiarepletion is metabolically active treatment

The easiest way to take in more vitamin B12 is by enriching your diet with certain foods, not supplements.

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Cyanocobalamin supplementation (6g/day) was associated with improved B12 biomarkers, with a potential to improve preconception B12 status in South Asian women.