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Description
A lack of intracellular cysteine, GSH, or SLC7A11 suppression reduces GPX4 activity, which can enhance lipid peroxidation and trigger ferroptosis (47)

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Similar findings were also observed in neuron-specific GCL knockdown mouse by Fernandez-Fernandez et al
Oral Microbiol

CNS redox homeostasis and dysfunction in neurodegenerative diseases
Boyette-Davis and Dougherty, 2014)
