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We have screened a number of TGR inhibitors and identified potential lead compounds for novel drug development

We then compared the production of thiomethyl metabolites after exposure to APAP, and 3 of its potential direct precursors: the glutathione conjugate (APAP-SG), APAP-Cys, and NAC-APAP for 24h in HRG cells and PHH (Fig
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First, GST weakens the efficacy of chemotherapy drugs by promoting their in vitro extrusion
