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Front Physiol 14:1154374 Chiasson JL, Naditch L, Miglitol Canadian University Investigator Group (2001) The synergistic effect of miglitol plus metformin combination therapy in the treatment of type 2 diabetes

Exercise robustly improves mitochondrial function, endothelial health, and myokine-mediated cross-talk between muscle, adipose tissue, and the brain, while vitamin D, acting through the vitamin D receptor (VDR), modulates calcium homeostasis, immune signaling, and tissue-specific metabolic responsiveness

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however, the commercial production from these approaches is not sufficiently cost-effective

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