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The concentrating capacity is dependent on the renal medulla.27 The degree of medullary concentration is established primordially by the renal tubules in the loop of Henle and the blood vessels surrounding it (vasa recta) during the countercurrent exchange process

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Anti-infective agents: ectoparasiticides (chlorinated hydrocarbons, pyrethins, sulfurated compounds), anthelmintics, antiprotozoal agents, antimalarial agents, antiamebic agents, antileiscmanial drugs, antitrichomonal agents, antitrypanosomal agents, sulfonamides, antimycobacterial drugs, antiviral chemotherapeutics and other antiviral agents as disclosed in U

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A particular type of cancer known as Malignant peripheral nerve sheath tumors (MPNST), which develops in association with NF-1, generally leads to poor survival

After washing with 1 ml PBS solution, cells were further crosslinked with 3 mM disuccinimidyl glutarate (Fisher Scientific) in 2.5 ml PBS solution at 30 C for 40 min