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However, a 2017 meta-analysis looking at almost 8,000 studies found only two brain training programs had more than one study in their favor (BrainHQ and CogniFit), and theres no evidence to support them as a preventative or treatment strategy.56 Ultimately, playing brain games wont make a huge difference in your cognition, but it can help you flex some skills better than another round of Candy Crush

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Neurotoxic Triad Excitotoxicity, Oxidative Stress and Neuroinflammation Excitotoxicity occurs when abnormally high levels of glutamate are in the synaptic cleft between neurons, leading to prolonged activation of glutamate receptors, such as the NMDA receptor, resulting in increased calcium influx into the postsynaptic neuron and resultant cell death (Olney, 1990)