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An inclusion of long COVID participants with predominant fatigue allowed an exploration of such changes in a different condition where fatigue is one of the main symptoms
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Zhuang et al

Always proceed with extreme caution and thorough preliminary research when combining agents
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Violation of the integrity of the intestinal barrier and its improper functioning can result in the uncontrolled passage of bacterial components, products of bacterial metabolism, and harmful substances, thus leading to systemic inflammation
